Structure of PDB 7zlu Chain B Binding Site BS03

Receptor Information
>7zlu Chain B (length=278) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSFKD
FIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLSL
DKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWKTG
YWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLANL
DQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPMTKEP
KLDRARRQVPEWTKYDEEIAELARRVRE
Ligand information
Ligand IDPDO
InChIInChI=1S/C3H8O2/c4-2-1-3-5/h4-5H,1-3H2
InChIKeyYPFDHNVEDLHUCE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(CO)CO
ACDLabs 11.02
CACTVS 3.352		OCCCO
FormulaC3 H8 O2
Name1,3-PROPANDIOL
ChEMBLCHEMBL379652
DrugBankDB02774
ZINCZINC000001529437
PDB chain7zlu Chain B Residue 1504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zlu A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
Resolution2.049 Å
Binding residue
(original residue number in PDB)		R1333 E1335 S1424 D1425
Binding residue
(residue number reindexed from 1)		R138 E140 S229 D230
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7zlu, PDBe:7zlu, PDBj:7zlu
PDBsum7zlu
PubMed37822503
UniProtG0SB58

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