Structure of PDB 7zgp Chain B Binding Site BS03

Receptor Information
>7zgp Chain B (length=93) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLIHPDTAKYPFKFEPFLRQEYSFSLDPDRPICEFYNSREGPKSCPRGPL
CPKKHVLPIFQNKIVCRHWLRGLCKKNDQCEYLHEYNLRKMPE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7zgp Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zgp Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
C34 C46 C52 H56
Binding residue
(residue number reindexed from 1)
C33 C45 C51 H55
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006397 mRNA processing
GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7zgp, PDBe:7zgp, PDBj:7zgp
PDBsum7zgp
PubMed35584695
UniProtQ06102|YTH1_YEAST mRNA 3'-end-processing protein YTH1 (Gene Name=YTH1)

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