Structure of PDB 7y7r Chain B Binding Site BS03

Receptor Information
>7y7r Chain B (length=897) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AALRNIWPKFPKWHEAPLAVAWEVTRFMHKVDSLGLKYDPSTARDVTDIE
KPPNDVFVTAMTGNFESKGSAVVLSAVLDYNPDNSPLYLVKLKPLMFEQG
CRLTRRFGPDRFFEILIPSPTSSPSVPPVSKQAVEEVIQWLTMGQHSLVG
RQWRAFFAKDAGYRKPPIIKERVHFFAETGITFRPDEPVEQRTEFKVSQM
LDWLLQLDNNTWQPHLKLFSRIQLGLSKTYAIMTLEPHQIRHHKTDLLSP
SGTGEVMNDGVGRMSRSVAKRIRDVLGLGDVPSAVQGRFGSAKGMWVIDV
DDTGDEDWIETYPSQRKWECDFVDKHQRTLEVRSVASELKSAGLNLQLLP
VLEDRARDKVKMRQAIGDRLINDLQRQFSEQKHALNRPVEFRQWVYESYS
SRATRVSHGRVPFLAGLPDSQEETLNFLMNSGFDPKKQKYLQDIAWDLQK
RKCDTLKSKLNIRVGRSAYIYMIADFWGVLEENEVHVGFSSKFRDEESFT
LLSDCDVLVARSPAHFPSDIQRVRAVFKPELHSLKDVIIFSTKGDVPLAK
KLSGGDYDGDMAWVCWDPEIVDGFVNAEMPLEPDLSRYLKKDKTTFKQLM
ASHGTGSAAKEQTTYDMIQKSFHFALQPNFLGMCTNYKERLCYINNSVSN
KPAIILSSLVGNLVDQSKQGIVFNEASWAQLRRELLGGALSLPDPMYKSD
SWLGRGEPTHIIDYLKFSIARPAIDKELEAFHNMKAADGAHFWDPDLASY
YTFFKEISDKSRSSALLFTTLKNRIGEVEKEYGRLVKKEDPYPVRVNQVY
EKWCAITPSKVIRLLELSFLADREMNTWALLRASTAFKLYYHKSPKFVWQ
MAGRQLAYIKAQMTSRPGEGAPALMTAFMYAGLMPDKKFTKQYVARL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7y7r Chain B Residue 1503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y7r Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D1007 D1009 D1011
Binding residue
(residue number reindexed from 1)		D556 D558 D560
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:7y7r, PDBe:7y7r, PDBj:7y7r
PDBsum7y7r
PubMed36039765
UniProtQ9Y7G6

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