Structure of PDB 7xt4 Chain B Binding Site BS03

Receptor Information
>7xt4 Chain B (length=1263) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPFYF
GVQQPSDSIPGKEHTSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGC
NVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVE
DGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWL
GGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESS
LPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISAL
TEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGD
LGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVA
IDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTA
LSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMINKTGPINNDYV
HPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGKI
NCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSELR
GMLRTHFEALTKSCFAIFGEDSTKTLGGKLDKALHPCTGLSDGLCPGCHL
FGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIP
DDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFS
FDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHT
FKIDKIKRVPQSDIREYINKGYQKLIEWSGNNVLPQWHVIPHIDKLYKLL
WVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKLGDKDNLPYKTRVK
GLTTPWSPWNPFQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xt4 Chain B Residue 1801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xt4 Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution3.08 Å
Binding residue
(original residue number in PDB)		C127 C130
Binding residue
(residue number reindexed from 1)		C123 C126
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7xt4, PDBe:7xt4, PDBj:7xt4
PDBsum7xt4
PubMed36306795
UniProtA0A0B0EGF3

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