Structure of PDB 7xsr Chain B Binding Site BS03

Receptor Information
>7xsr Chain B (length=1287) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSF
LRKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFS
NFDLDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGT
YTGRITLRNEHAKKLLLASLGFVDKLCGALCRIEVIKSEDHNDELRKQAE
VIVEAFKQNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHH
LWDIKVQGTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVS
TRFRILGDTEYYSKAHDSEGSDLFIPVTPPEGIETKEWIIVGRLKAATPF
YFGVQQPSDSIPGKEKKSEDSLVINEHTSFNILLDKENRYRIPRSALRGA
LRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIR
YRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRY
WEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMR
GKEKELLEMGESSLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEV
GSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNAIEPEPRFAVKSETHR
GIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGN
EFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKK
GFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKE
MINKTEGPINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDII
THEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKFF
NINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTKTLGGKLDKALHP
CTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNPERSLT
LGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRETVQPER
NVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLGKGKPY
GFGSVKIKIDSLHTFKINSNNDKIKRVPQSDIREYINKGYQKLIEWSGNN
SIQKGNVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGY
IEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xsr Chain B Residue 1803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xsr Target RNA activates the protease activity of Craspase to confer antiviral defense.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		H747 C750 C752
Binding residue
(residue number reindexed from 1)		H719 C722 C724
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7xsr, PDBe:7xsr, PDBj:7xsr
PDBsum7xsr
PubMed36306795
UniProtA0A0B0EGF3

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