Structure of PDB 7x4q Chain B Binding Site BS03

Receptor Information
>7x4q Chain B (length=294) Species: 446 (Legionella pneumophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDWEQTFRKWSKPSSETESTKAENAERMIKAAINSSQILSTKDISVFPQG
SYRNNTNVREDSDVDICVCLNTLVLSDYSLVPGMNDKLAESYTYKQFKSD
LETALKNKFGTLGVSRGDKAFDVHANSYRVDADVVPAIQGRLYYDKNHNA
FIRGTCIKPDSGGTIYNWPEQNYSNGVNKNKSTGNRFKLIVRAIKRLRNH
LAEKGYNTAKPIPSYLMECLVYIVPDQYFTGDSYKTNVENCINYLYNQID
SSDWTEINEIKYLFGSHQMWNKTQVKEFLLTAWSYIQKNLEHHH
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7x4q Chain B Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7x4q Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		D67 D139
Binding residue
(residue number reindexed from 1)		D65 D133
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7x4q, PDBe:7x4q, PDBj:7x4q
PDBsum7x4q
PubMed37604815
UniProtP0DSP3|CDNE2_LEGPN Cyclic dipyrimidine nucleotide synthase CdnE (Gene Name=cdnE02)

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