Structure of PDB 7und Chain B Binding Site BS03

Receptor Information
>7und Chain B (length=1122) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EITPDLWQEACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPI
DLPPRYLLKFEQIYLSKPTHWEDGAPSPMMPNEARLRNLTYSAPLYVDIT
KTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPL
DPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSKYAYTGECRSCLENSS
RPTSTIWVSMLARIGQRIVATLPYIKQEVPIIIVFRALGFVSDRDILEHI
IYDFEDPEMMEMVKPSLDEAFVIQEQNVALNFIGSRGAKPGVTKEKRIKY
AKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHY
GNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTR
IISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSP
IGRDGKLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQP
SPILEFLEEWSMENLEEISPAAIADATKIFVNGCWVGIHKDPEQLMNTLR
KLRRQMDIIVSEVSMIRDIREREIRIYTDAGRICRPLLIVEKQKLLLKKR
HIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVA
YCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMGVYIT
NFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGY
NQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQ
GMRHAIYDKLDDDGLIAPGVRVSGDDVIIGKTVTLTKRDCSTFLRTSETG
IVDQVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQE
DMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF
NDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLK
HMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQF
LRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQISLVRMP
YACKLLFQELMSMSIAPRMMSV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7und Chain B Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7und Structural basis of nucleosome retention during transcription elongation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
C1119 C1122 C1137
Binding residue
(residue number reindexed from 1)
C1067 C1070 C1085
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005654 nucleoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7und, PDBe:7und, PDBj:7und
PDBsum7und
PubMed35709268
UniProtA0A4X1TVZ5

[Back to BioLiP]