Structure of PDB 7t80 Chain B Binding Site BS03

Receptor Information
>7t80 Chain B (length=209) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDPVLLNLPMNVTISENSPVSSFVAHVLASDLLTFNITAGNRERAFFINA
TTGIVTVNRPLDRERIPEYRLTVSVKDNPENPRIARKDFDLLLVSLADEN
DNHPLFTEGTYQAEVMENSPAGTPLTVLNGPILALDADEDVYAVVTYQLL
GTHSDLFVIDNSTGVVTVRSGIIIDREAFSPPFLELLLLAEDIGQLNGTA
HLFITILDD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7t80 Chain B Residue 2103 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7t80 Crystal Structure of Mouse Cadherin-23 EC18-19
Resolution2.301 Å
Binding residue
(original residue number in PDB)		N1930 N1932 D1966 D1968 Y1972 D2022
Binding residue
(residue number reindexed from 1)		N100 N102 D136 D138 Y142 D192
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t80, PDBe:7t80, PDBj:7t80
PDBsum7t80
PubMed
UniProtQ99PF4|CAD23_MOUSE Cadherin-23 (Gene Name=Cdh23)

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