Structure of PDB 7rua Chain B Binding Site BS03

Receptor Information

>7rua Chain B (length=305) Species: 7955 (Danio rerio)

EPLEPTLKNIIEQKSLKWIFVGGKGGVGKTTCSCSLAVQLAAVRESVLII
STNPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEE
DNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTG
HTLRLLNFPTIVERGLGRLMQIKNQDQLASKLEETLPVIRSVSEQFKDPE
QTTFICVCIAEFLSLYETERLIQELAKCRIDTHNIIVNQLVFPDNERPCK
MCEARHKIQSKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSKQLLE
PYSPP

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7rua Chain B Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7rua Structural insights into metazoan pretargeting GET complexes.
• Resolution: 3.4 Å
• Binding residue (original residue number in PDB): T45 D160
• Binding residue (residue number reindexed from 1): T30 D145
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.-.-

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
• GO:0007416 synapse assembly
• GO:0045048 protein insertion into ER membrane
• GO:0071816 tail-anchored membrane protein insertion into ER membrane

Cellular Component

• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum
• GO:0043529 GET complex

External links

• PDB: RCSB:7rua, PDBe:7rua, PDBj:7rua
• PDBsum: 7rua
• PubMed: 34887561
• UniProt: Q6IQE5|GET3_DANRE ATPase GET3 (Gene Name=get3)