Structure of PDB 7q4i Chain B Binding Site BS03

Receptor Information
>7q4i Chain B (length=281) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HENSTIAERLYSEVRVLCWIMTNPSNHQKKARHVKRTWGKRCNKLIFMSS
AKDDELDAVALPVGEGRNNLWGKTKEAYKYIYEHHINDADWFLKADDDTY
TIVENMRYMLYPYSPETPVYFGCKFKPYVKQGYMSGGAGYVLSREAVRRF
VVEALPNPKLCKSDNSGAEDVEIGKCLQNVNVLAGDSRDSNGRGRFFPFV
PEHHLIPSHTDKKFWYWQYIFYKTDEGLDCCSDNAISFHYVSPNQMYVLD
YLIYHLRPYGIINTPDALPNKLAVGELMPEI
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7q4i Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7q4i Structural basis for the synthesis of the core 1 structure by C1GalT1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		D181 D183 H324
Binding residue
(residue number reindexed from 1)		D96 D98 H239
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.122: N-acetylgalactosaminide beta-1,3-galactosyltransferase.
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7q4i, PDBe:7q4i, PDBj:7q4i
PDBsum7q4i
PubMed35504880
UniProtQ7K237|C1GLT_DROME Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (Gene Name=C1GalTA)

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