Structure of PDB 7pr1 Chain B Binding Site BS03

Receptor Information

>7pr1 Chain B (length=587) Species: 759272 (Thermochaetoides thermophila DSM 1495)

ADWAIIKQMSRYLWPKDSWSDKARVLLALSLLVGGKVLNVHVPFYFREII
DRLNIDVAAVGGTVSAVAGAVIFAYGASRIGAVVSQELRNAVFSSVAQKA
IRRVATQTFGHLLNLDLSFHLSKQTGGLTRAIDRGTKGISYLLTSMVFHI
VPTALEIGMVCGILTYQFGWEFAAITAATMAAYTAFTITTTAWRTKFRRQ
ANAADNAASTVAVDSLINYEAVKYFNNEAYEIARYDKALQAYERSSIKVA
TSLAFLNSGQNIIFSSALTLMMWLGARGVLAGDLSVGDLVLINQLVFQLS
VPLNFLGSVYRELRQSLLDMETLFDLQKVNVTIREAPNAKPLALPKGGEI
RFENVTFGYYPDRPILRNLSLTIPAGKKVAVVGPSGCGKSTLLRLLFRSY
DPQQGKIFIDDQDIKSVTLESLRKSIGVVPQDTPLFNDTVELNIRYGNVN
ATQEQVIAAAQKAHIHEKIISWPHGYQTRVGERGLMISGGEKQRLAVSRL
ILKDPPLLFFDQATSALDTHTEQALMANINEVVKEKKRTALFVAHRLRTI
YDADLIIVLKEGVVVEQGSHRELMERDGVYAELWMAQ

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 7pr1 Chain B Residue 802

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7pr1 Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.
• Resolution: 2.81 Å
• Binding residue (original residue number in PDB): Q522 D602 Q603
• Binding residue (residue number reindexed from 1): Q431 D511 Q512
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:0042626 ATPase-coupled transmembrane transporter activity
• GO:0140359 ABC-type transporter activity

Biological Process

• GO:0006879 intracellular iron ion homeostasis
• GO:0055085 transmembrane transport

Cellular Component

• GO:0005743 mitochondrial inner membrane
• GO:0016020 membrane

External links

• PDB: RCSB:7pr1, PDBe:7pr1, PDBj:7pr1
• PDBsum: 7pr1
• PubMed: 35896548
• UniProt: G0SBE6