Structure of PDB 7oiw Chain B Binding Site BS03

Receptor Information
>7oiw Chain B (length=327) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFRKNGLPYIMHPI
QVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIVDGV
TKLKENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQIRISRET
LEIYAPLAHHLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAY
IETAIDRIRTEMDRMNIEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLA
IRVIVNSINDCYAILGLVHTLWKPMPGRFKDYIAMPKQNLYQSLHTTVVG
PNGDPLEIQIRTFDMHEIAEHGVAAHW
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7oiw Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oiw Structure of S. aureus Rel catalytic domains in complex with pppGpp
Resolution2.63 Å
Binding residue
(original residue number in PDB)		H60 H84 D85 D151
Binding residue
(residue number reindexed from 1)		H48 H72 D73 D127
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.6.5: GTP diphosphokinase.
Gene Ontology
Biological Process
GO:0015969 guanosine tetraphosphate metabolic process

View graph for
Biological Process
External links
PDB RCSB:7oiw, PDBe:7oiw, PDBj:7oiw
PDBsum7oiw
PubMed
UniProtQ931Q4|RELA_STAAM GTP pyrophosphokinase (Gene Name=relA)

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