Structure of PDB 7n7g Chain B Binding Site BS03

Receptor Information
>7n7g Chain B (length=133) Species: 1352 (Enterococcus faecium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIKGINHITYSVSNIAKSIEFYRDILGADILVESETLAYFNLGGIWLALN
EEKNIPRSEIKYSYTHIAFTISDNDFEDWYNWLKENEVNILERDKKSIYF
TDLDGHKLELHTGSLEDRLSYYKEAKPHMNFYI
Ligand information
Ligand IDFCN
InChIInChI=1S/C3H7O4P/c1-2-3(7-2)8(4,5)6/h2-3H,1H3,(H2,4,5,6)/t2-,3+/m0/s1
InChIKeyYMDXZJFXQJVXBF-STHAYSLISA-N
SMILES
SoftwareSMILES
CACTVS 3.341C[C@@H]1O[C@@H]1[P](O)(O)=O
OpenEye OEToolkits 1.5.0C[C@H]1[C@H](O1)P(=O)(O)O
ACDLabs 10.04O=P(O)(O)C1OC1C
OpenEye OEToolkits 1.5.0CC1C(O1)P(=O)(O)O
CACTVS 3.341C[CH]1O[CH]1[P](O)(O)=O
FormulaC3 H7 O4 P
NameFOSFOMYCIN;
1,2-EPOXYPROPYLPHOSPHONIC ACID
ChEMBLCHEMBL1757
DrugBankDB00828
ZINCZINC000001530427
PDB chain7n7g Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7n7g Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Y64 H66 Y105 R124
Binding residue
(residue number reindexed from 1)		Y64 H66 Y99 R118
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0046872 metal ion binding
Biological Process
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7n7g, PDBe:7n7g, PDBj:7n7g
PDBsum7n7g
PubMed34882867
UniProtF1C939

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