Structure of PDB 7mi9 Chain B Binding Site BS03

Receptor Information
>7mi9 Chain B (length=338) Species: 243231 (Geobacter sulfurreducens PCA) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLPLYVQSPKAYVRKDGDCLVIEEERVRVAEARLGETSQVALFGNATLTT
AALHECLRREIPVTWLSYGGWFMGHTVSTGHRNVETRTYQYQRSFDPETC
LNLARRWIVAKIANCRTLLRRNWRGEGDEAKAPPGLLMSLQDDMRHAMRA
PSLEVLLGIEGASAGRYFQHFSRMLRGGDGEGMGFDFTTRNRRPPKDPVN
ALLSFAYAMLTREWTVALAAVGLDPYRGFYHQPRFGRPALALDMMEPFRP
LIADSTVLMAINNGEIRTGDFVRSAGGCNLTDSARKRFIAGFERRMEQEV
THPIFKYTISYRRLLEVQARLLTRYLSGEIPAYPNFVT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7mi9 Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas.
Resolution3.89 Å
Binding residue
(original residue number in PDB)		L377 E380 G381 A384 G385 F388 Q389 F407 T408 R410 R412
Binding residue
(residue number reindexed from 1)		L157 E160 G161 A164 G165 F168 Q169 F187 T188 R190 R192
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7mi9, PDBe:7mi9, PDBj:7mi9
PDBsum7mi9
PubMed34588691
UniProtQ74H36|CS4F1_GEOSL CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion (Gene Name=cas4-cas1)

[Back to BioLiP]