Structure of PDB 7go5 Chain B Binding Site BS03

Receptor Information
>7go5 Chain B (length=180) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPGFDFAQAIMKKNTVIARTEKGEFTMLGVYDRVAVIPTHASVGEIIYIN
DVETRVLDACALRDLTDTNLEITIVKLDRNQKFRDIRHFLPRCEDDYNDA
VLSVHTSKFPNMYIPVGQVTNYGFLNLGGTPTHRILMYNFPTRAGQCGGV
VTTTGKVIGIHVGGNGAQGFAAMLLHSYFT
Ligand information
Ligand IDTZ9
InChIInChI=1S/C9H6F2O/c10-7-4-6-2-1-3-12-9(6)8(11)5-7/h1-2,4-5H,3H2
InChIKeyDRQKJKGKLYCHHB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7c1c(cc(c2c1C=CCO2)F)F
ACDLabs 12.01
CACTVS 3.385		Fc1cc(F)c2OCC=Cc2c1
FormulaC9 H6 F2 O
Name6,8-bis(fluoranyl)chromene
ChEMBL
DrugBank
ZINCZINC000039941619
PDB chain7go5 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7go5 PanDDA analysis group deposition
Resolution1.5 Å
Binding residue
(original residue number in PDB)		V34 D58 A59 C60 I74
Binding residue
(residue number reindexed from 1)		V34 D58 A59 C60 I74
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7go5, PDBe:7go5, PDBj:7go5
PDBsum7go5
PubMed
UniProtQ68T42|POLG_HED68 Genome polyprotein

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