Structure of PDB 7dw5 Chain B Binding Site BS03
Receptor Information
>7dw5 Chain B (length=131) Species:
9606
(Homo sapiens) [
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RRRRLVWTPSQSEALRACFERNPYPGIATRERLAQAIGIPEPRVQIWFQN
ERSRQLRQHRRESRPWPGRRGPPEGRRKRTAVTGSQTALLLRAFEKDRFP
GIAAREELARETGLPESRIQIWFQNRRARHP
Ligand information
>7dw5 Chain C (length=21) [
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cgacttgatgagattagactg
Receptor-Ligand Complex Structure
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PDB
7dw5
DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Resolution
2.83 Å
Binding residue
(original residue number in PDB)
R23 Y43 Q68
Binding residue
(residue number reindexed from 1)
R4 Y24 Q49
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
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Molecular Function
External links
PDB
RCSB:7dw5
,
PDBe:7dw5
,
PDBj:7dw5
PDBsum
7dw5
PubMed
34699692
UniProt
P0CJ85
|DU4L2_HUMAN Double homeobox protein 4-like protein 2 (Gene Name=DUX4L2)
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