Structure of PDB 7ckf Chain B Binding Site BS03

Receptor Information
>7ckf Chain B (length=256) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLM
NKLAGKNKGFSVASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVE
KADNKNDIQIFALALLLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLPDL
VWTLRDFCLGLEIDGQLVTPDEYLENSLRPFPKKKCFIFDLPAHQKKLAQ
LETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLT
YVNAIS
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain7ckf Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ckf Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Resolution2.284 Å
Binding residue
(original residue number in PDB)		Y47 R48 K51 T75 G100
Binding residue
(residue number reindexed from 1)		Y42 R43 K46 T70 G95
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:7ckf, PDBe:7ckf, PDBj:7ckf
PDBsum7ckf
PubMed33876762
UniProtQ96PP8|GBP5_HUMAN Guanylate-binding protein 5 (Gene Name=GBP5)

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