Structure of PDB 7c6l Chain B Binding Site BS03

Receptor Information
>7c6l Chain B (length=416) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTLEVWIMPNSPQPAEDFKALVAPFEKAHGVEVKVTVLDWGVAWTKITTA
ATSGVGPDLTQLGTTWVGAISAMGVLEPVDDVLEALGGEKAYLPAVWRTT
RLEGARQATAVPWFSELRAFYYRTDALKAAGVNPAEMFASWQGFEAGLAR
LKASSFRDPETKAPLAPLCTPGRTPRTLHNAAPWIWGAGGEIVRQAGGRW
QSALNSPESLEGLYFFLSLAQKGYVPAESLEKNTAQIEADFQAGKCAVFA
SGPWMIQRAQVPEAKGGFAERTAAKNLGVAPYPAGPKGRYTFFGGSNLAL
FNFSKNKPLAKELLKYLGGPEAQVRYAQMTGMLPALRSAWSDPSFQQNPL
LRTFIQAAQFGRTYPSLAGWGGVENLAVQHLGMAWDLVAQGRLTREALKD
LMDKASAAINQALRHH
Ligand information
Ligand IDZ6H
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4-,5+,6+/m0/s1
InChIKeyWQZGKKKJIJFFOK-FQJSGBEDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.7.6C([C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-L-altropyranose;
alpha-L-altrose;
L-altrose;
altrose
ChEMBL
DrugBank
ZINCZINC000000896167
PDB chain7c6l Chain D Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c6l Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		G64 T65 T66 W67 E117 H180 G296
Binding residue
(residue number reindexed from 1)		G63 T64 T65 W66 E116 H179 G295
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:1901982 maltose binding
Biological Process
GO:0015768 maltose transport
GO:0042956 maltodextrin transmembrane transport
Cellular Component
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7c6l, PDBe:7c6l, PDBj:7c6l
PDBsum7c6l
PubMed32866452
UniProtQ53W80

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