Structure of PDB 7c6j Chain B Binding Site BS03

Receptor Information
>7c6j Chain B (length=416) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTLEVWIMPNSPQPAEDFKALVAPFEKAHGVEVKVTVLDWGVAWTKITTA
ATSGVGPDLTQLGTTWVGAISAMGVLEPVDDVLEALGGEKAYLPAVWRTT
RLEGARQATAVPWFSELRAFYYRTDALKAAGVNPAEMFASWQGFEAGLAR
LKASSFRDPETKAPLAPLCTPGRTPRTLHNAAPWIWGAGGEIVRQAGGRW
QSALNSPESLEGLYFFLSLAQKGYVPAESLEKNTAQIEADFQAGKCAVFA
SGPWMIQRAQVPEAKGGFAERTAAKNLGVAPYPAGPKGRYTFFGGSNLAL
FNFSKNKPLAKELLKYLGGPEAQVRYAQMTGMLPALRSAWSDPSFQQNPL
LRTFIQAAQFGRTYPSLAGWGGVENLAVQHLGMAWDLVAQGRLTREALKD
LMDKASAAINQALRHH
Ligand information
Ligand IDFJO
InChIInChI=1S/C3H8O4/c4-2-1-3(5,6)7/h4-7H,1-2H2
InChIKeyVQAQNRIKRHUZBR-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7C(CO)C(O)(O)O
CACTVS 3.385OCCC(O)(O)O
FormulaC3 H8 O4
Namepropane-1,1,1,3-tetrol
ChEMBL
DrugBank
ZINC
PDB chain7c6j Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7c6j Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D40 G42 P176 R177
Binding residue
(residue number reindexed from 1)		D39 G41 P175 R176
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:1901982 maltose binding
Biological Process
GO:0015768 maltose transport
GO:0042956 maltodextrin transmembrane transport
Cellular Component
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7c6j, PDBe:7c6j, PDBj:7c6j
PDBsum7c6j
PubMed32866452
UniProtQ53W80

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