Structure of PDB 7b0c Chain B Binding Site BS03

Receptor Information
>7b0c Chain B (length=144) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLTKFTDLALRSLMRLAVVRDGDEPLATREVAEVVGVPYTHAAKAITRL
QHLGVVEARRGRGGGLTLTDLGRRVSVGWLVRELEGEAEVVDCEGDNPCP
LRGACRLRRALRDAQEAFYAALDPLTVTDLVAAPTGPVLLGLTD
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain7b0c Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7b0c Structural determinants of DNA recognition by the NO sensor NsrR and related Rrf2-type [FeS]-transcription factors.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D8 R12
Binding residue
(residue number reindexed from 1)		D8 R12
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7b0c, PDBe:7b0c, PDBj:7b0c
PDBsum7b0c
PubMed35908109
UniProtQ9L132|NSRR_STRCO HTH-type transcriptional repressor NsrR (Gene Name=nsrR)

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