Structure of PDB 6xfr Chain B Binding Site BS03

Receptor Information

>6xfr Chain B (length=216) Species: 400092 (Pontibacter korlensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QQLEVTKISSKVWIHTSYKTYHGTVVPSHGLIVSTKEGAVLIDTGWGKEP
TEELLTWIKTNLKQPVKVCVPTHWHDDKLGGMEAVQRQGVPVVTSELTAI
LAAENSKGTPDVTFATDTTFAIGGQQLEVYFPGGGHTADNVVVYLPQQKI
LFGGCLVKDLQAKNLGNTADADLKSWPLAIQRLQQRYPKAKVVVPSHGPW
GDQSLLSHTLSLLQNQ

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6xfr Chain B Residue 308 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6xfr Metallo-beta-lactamase from Pontibacter korlensis
Resolution	2.608 Å
Binding residue (original residue number in PDB)	L150 P151 Q152
Binding residue (residue number reindexed from 1)	L145 P146 Q147
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	H78 H80 D82 H141 C160 K163 N172 H202
Catalytic site (residue number reindexed from 1)	H73 H75 D77 H136 C155 K158 N167 H197
Enzyme Commision number	3.5.2.6: beta-lactamase.

Gene Ontology

	Molecular Function
GO:0008270	zinc ion binding
GO:0008800	beta-lactamase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

	Biological Process
GO:0017001	antibiotic catabolic process
GO:0046677	response to antibiotic

	Cellular Component
GO:0042597	periplasmic space

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Cellular Component

External links

PDB	RCSB:6xfr, PDBe:6xfr, PDBj:6xfr
PDBsum	6xfr
PubMed
UniProt	A0A0E3ZJD7

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