Structure of PDB 6wu7 Chain B Binding Site BS03

Receptor Information
>6wu7 Chain B (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKV
PYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPR
DLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGELSAEEVSLVCQHVLD
EADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6wu7 Chain B Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wu7 CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Resolution1.84 Å
Binding residue
(original residue number in PDB)		Q17 D18 T20
Binding residue
(residue number reindexed from 1)		Q13 D14 T16
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:6wu7, PDBe:6wu7, PDBj:6wu7
PDBsum6wu7
PubMed34089643
UniProtQ96Q77|CIB3_HUMAN Calcium and integrin-binding family member 3 (Gene Name=CIB3)

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