Structure of PDB 6vv5 Chain B Binding Site BS03

Receptor Information
>6vv5 Chain B (length=1097) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NFRRFFSKFNVQAPAVVVLGGYLPIVHGIFVSGFEIGISQPSGYQLYLHK
ATTARLRICQFPSNCLFNKAIPAHVVGITWDNDRVTVFSDKIYYFYFKND
WSRVATAMQYVYEPTYYMLNVTSAGEDGISYQPCTANCIGYAANVFATEP
NGHIPEGFSFNNWFLLSNDSTLVHGKVVSNQPLLVNCLLAIPKIYQFFSF
NQTIDGVCNGAAVQRAPEALRFNINDISVILASIVLHTALGTNFSFVCSN
SSNPHLATPYYCFLKVDTYNSTVYKFLAVLPPTVREIVITKYGDVYVNGF
GYLHLGLLDAVTINFTGFWTIASTNFVDALIEVQGTAIQRILYCDDPVSQ
LKCSQVAFDLDDGFYTISSREQPISFVTLPSFNDHSFVNITVSASFGANL
IASDTTINGFSSFCVDTRQFTISLFYNVTNVSKSQDSNCPFTLQSVNDYL
SFSKFCVSTSLLASACTIDLFGYPESGVKFTSLYFQFTKGELITGTPKPF
EGVTDVSFMTLDVCTKYTIYGFKGEGIITLTNSSFLAGVYYTSDSGQLLA
FKNVTSGAVYSVTPCSFSEQAAYVDDDIVGVISSLSSSTFNSTRELPGFF
YHSNDGSNCTEPVLVYSNIGVCKSGSIGYVPSQSGQVKIAPTVTGNISIP
TNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQYTAACKTIES
ALQLSARLESVEVNSMLTISDEALQLATISSFNGDGYNFTNVLGVSVVQK
RSFIEDLLFNKVVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKL
HMYSASLIGGMVLGGFTSAAALPFSYAVQARLNYLALQTDVLQRNQQLLA
ESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGAALT
QLTVQLQHNFQAISSSIDDIYSRLDILSADAQVDRLITGRLSALNAFVAQ
TLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFSLVQAAPQG
LLFLHTVLVPSDFVDVIAIAGLCVNDEIALTLREPGLVLFTHEEYFVSSR
RMFEPRKPTVSDFVQIESCVVTYVNLTRDQLPDVIPDYIDVNKTLDE
Ligand information
Ligand IDPAM
InChIInChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h7-8H,2-6,9-15H2,1H3,(H,17,18)/b8-7-
InChIKeySECPZKHBENQXJG-FPLPWBNLSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCCC\C=C/CCCCCCCC(=O)O
ACDLabs 10.04O=C(O)CCCCCCC\C=C/CCCCCC
CACTVS 3.341CCCCCCC=CCCCCCCCC(O)=O
OpenEye OEToolkits 1.5.0CCCCCCC=CCCCCCCCC(=O)O
CACTVS 3.341CCCCCC\C=C/CCCCCCCC(O)=O
FormulaC16 H30 O2
NamePALMITOLEIC ACID
ChEMBLCHEMBL453509
DrugBankDB04257
ZINCZINC000008221009
PDB chain6vv5 Chain B Residue 1406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vv5 Structure and immune recognition of the porcine epidemic diarrhea virus spike protein.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F347 A389 L391 P392 V408 F411 Y413
Binding residue
(residue number reindexed from 1)		F246 A278 L280 P281 V297 F300 Y302
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0033644 host cell membrane
GO:0044173 host cell endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0055036 virion membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6vv5, PDBe:6vv5, PDBj:6vv5
PDBsum6vv5
PubMed33378641
UniProtS5RJN4

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