Structure of PDB 6v82 Chain B Binding Site BS03

Receptor Information
>6v82 Chain B (length=391) Species: 272561 (Chlamydia trachomatis D/UW-3/CX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FKHKHPFGGAFLPEELLAPIQNLKAEWEILKTQQSFLSELDCILKNYAGR
QTPLTEVKNFARAIDGPRVFLKREDLLHTGAHKLNNALGQCLLAKYLGKT
RVVAETGAGQHGVATATACAYLGLDCVVYMGAKDVERQKPNVEKMRFLGA
EVVSVTKGSCGLKDAVNQALQDWATTHSFTHYCLGSALGPLPYPDIVRFF
QSVISAEVKEQIHAVAGRDPDILIACIGGGSNAIGFFHHFIPNPKVQLIG
VEGGGLGISSGKHAARFATGRPGVFHGFYSYLLQDDDGQVLQTHSISAGL
DYPSVGPDHAEMHESGRAFYTLATDEEALRAFFLLTRNEGIIPALESSHA
LAHLVSIAPSLPKEQIVIVNLSGRGDKDLPQIIRRNRGIYE
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain6v82 Chain D Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6v82 Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
Resolution2.424 Å
Binding residue
(original residue number in PDB)		R102 E152 V154
Binding residue
(residue number reindexed from 1)		R101 E151 V153
Annotation score1
Enzymatic activity
Enzyme Commision number 4.2.1.20: tryptophan synthase.
Gene Ontology
Molecular Function
GO:0004834 tryptophan synthase activity
GO:0016829 lyase activity
Biological Process
GO:0000162 tryptophan biosynthetic process
GO:0006568 tryptophan metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v82, PDBe:6v82, PDBj:6v82
PDBsum6v82
PubMed34107106
UniProtO84172|TRPB_CHLTR Tryptophan synthase beta chain (Gene Name=trpB)

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