Structure of PDB 6uwn Chain B Binding Site BS03

Receptor Information

>6uwn Chain B (length=222) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SRHVVICGWSESTLECLRELRGSEVFVLAEDENVRKKVLRSGANFVHGDP
TRVSDLEKANVRGARAVIVDLESDSETIHCILGIRKIDESVRIIAEAERY
ENIEQLRMAGADQVISPFVISGRLMSRSIDDGYEAMFVQDVLAEESTRRM
VEVPIPEGSKLEGVSVLDADIHDVTGVIIIGVGRGDELIIDPPRDYSFRA
GDIILGIGKPEEIERLKNYISA

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6uwn Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6uwn Ball-and-chain inactivation in a calcium-gated potassium channel.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	G290 E326
Binding residue (residue number reindexed from 1)	G176 E212
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0008324	monoatomic cation transmembrane transporter activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

	Biological Process
GO:0006813	potassium ion transport
GO:0034220	monoatomic ion transmembrane transport
GO:0098655	monoatomic cation transmembrane transport

	Cellular Component
GO:0005886	plasma membrane

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Cellular Component

External links

PDB	RCSB:6uwn, PDBe:6uwn, PDBj:6uwn
PDBsum	6uwn
PubMed	32269335
UniProt	O27564\|MTHK_METTH Calcium-gated potassium channel MthK (Gene Name=mthK)

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