Structure of PDB 6tu2 Chain B Binding Site BS03

Receptor Information
>6tu2 Chain B (length=314) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGTITDASGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDVYEIKEAIKGAGT
DEACLIEILASRSNEHIRELNRAYKTEFKKTLEEAIRSDTSGHFQRLLIS
LSQGNRDESTNVDMSLVQRDVQELYAAGENRLGTDESKFNAILCSRSRAH
LVAVFNEYQRMTGRDIEKSICREMSGDLEQGMLAVVKCLKNTPAFFAERL
NKAMRGAGTKDRTLIRIMVSRSELDLLDIRAEYKRMYGKSLYHDITGDTS
GDYRKILLKICGGN
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6tu2 Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tu2 Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		C409 M412 S413 E417
Binding residue
(residue number reindexed from 1)		C221 M224 S225 E229
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding

View graph for
Molecular Function
External links
PDB RCSB:6tu2, PDBe:6tu2, PDBj:6tu2
PDBsum6tu2
PubMed32344647
UniProtQ5XI77

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