Structure of PDB 6s3n Chain B Binding Site BS03

Receptor Information

>6s3n Chain B (length=436) Species: 56957 (Thermus oshimai) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVG
TFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRL
QDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSH

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6s3n Chain B Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6s3n Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Resolution	2.533 Å
Binding residue (original residue number in PDB)	T98 D171
Binding residue (residue number reindexed from 1)	T32 D105
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003678	DNA helicase activity
GO:0016887	ATP hydrolysis activity

	Biological Process
GO:0000723	telomere maintenance
GO:0006281	DNA repair

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Molecular Function

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Biological Process

External links

PDB	RCSB:6s3n, PDBe:6s3n, PDBj:6s3n
PDBsum	6s3n
PubMed	33784404
UniProt	K7RJ88

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