Structure of PDB 6kdv Chain B Binding Site BS03

Receptor Information
>6kdv Chain B (length=283) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYLYVEHAVVEREAGGIGIYDQEGLTLAPVAGLGVLFLGPGTRITHAAVR
LLAENGCTVAWVGEGMARFYAQGLGDTRSAARFYRQARAWADPALHLEVV
MRLYRMRFSEPLPEGLTLEQVRGLEGVRVRNAYARWSRETGVPWYGRSYD
RGNWRAADPVNRALSAGASYLYGLAHAAIVSLGFSPALGFIHTGKLLSFV
YDIADLYKADYLVPAAFRTVAESEEAVERRVRRALREAIQEGRLLERMAE
DLLNLFRGLGLPTRPGGLWDLEGEVEGGVAYGG
Ligand information
Receptor-Ligand Complex Structure
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PDB6kdv Crystal structure of Cas1 in complex with branched DNA.
Resolution3.11 Å
Binding residue
(original residue number in PDB)
E31 R32 G35 R63 T65
Binding residue
(residue number reindexed from 1)
E11 R12 G15 R43 T45
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:6kdv, PDBe:6kdv, PDBj:6kdv
PDBsum6kdv
PubMed31792780
UniProtQ53WG8|CAS1B_THET8 CRISPR-associated endonuclease Cas1 2 (Gene Name=cas1-2)

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