Structure of PDB 6jub Chain B Binding Site BS03

Receptor Information
>6jub Chain B (length=544) Species: 5062 (Aspergillus oryzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPYLITGIPKDPKHPLPIRKDIDDWYLEQRIQLTLFVEALTVIQNRPLND
QLSYFRLAGIHGAPWTEWDGVPGGQKDSKGNPTGFAVHNNYTFPTWHRVY
VTLYEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFADELR
LPILVTMPMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAITSFD
LPFDKCQSTTKYGLLENYNADVWADGGQNWLRANLALNEHPWYQNLDGWD
SVPTLQDMTFRLLTTGGLNWGEFSSTRYAPKNWMNLEAIHNNVHNWVGGF
MFSRPGRHDLKLWGAGHMSSVPVAAYDPIFWLHHCNIDRLTAIWQTVNSG
SWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYDYAIT
KSRIRKEISDLYGQRTKEVYKDFEEDYILSIRYSRYALGGKPFQINIFFG
DVDGKDFYDARSQNFVGSVFNFSGVLSVSQLPARLAVHYYKKQNKGEVPT
PRYVVVNSQGKAEAEVKVEVALHKTEYRRVADGKRAEVDDAYRA
Ligand information
Ligand IDPER
InChIInChI=1S/O2/c1-2/q-2
InChIKeyANAIPYUSIMHBEL-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[O-][O-]
FormulaO2
NamePEROXIDE ION
ChEMBL
DrugBank
ZINC
PDB chain6jub Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6jub Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Resolution1.54 Å
Binding residue
(original residue number in PDB)		H67 H94 H103 H328 H332 H372 F513
Binding residue
(residue number reindexed from 1)		H61 H88 H97 H290 H294 H334 F472
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Gene Ontology
Molecular Function
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0042438 melanin biosynthetic process
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6jub, PDBe:6jub, PDBj:6jub
PDBsum6jub
PubMed32356371
UniProtA0A1S9DK56

[Back to BioLiP]