Structure of PDB 6iej Chain B Binding Site BS03

Receptor Information
>6iej Chain B (length=126) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SYSHVFTVTVRKATNVTKGAIGDMLDTPDPYVELFIPSAPDCRKRTKHFN
NDVNPVWNETFEFILDPNQDNVLEVTLMDANYVMDETLGMATFPISSLKL
GEKKEVQLTFNNVTEMTLELSLEVCS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6iej Chain B Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6iej Structural basis of phosphatidylcholine recognition by the C2-domain of cytosolic phospholipase A2alpha.
Resolution2.206 Å
Binding residue
(original residue number in PDB)		D40 T41 D43 N65
Binding residue
(residue number reindexed from 1)		D26 T27 D29 N51
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
3.1.1.5: lysophospholipase.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008289 lipid binding

View graph for
Molecular Function
External links
PDB RCSB:6iej, PDBe:6iej, PDBj:6iej
PDBsum6iej
PubMed31050338
UniProtP49147|PA24A_CHICK Cytosolic phospholipase A2 (Gene Name=PLA2G4A)

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