Structure of PDB 6czz Chain B Binding Site BS03

Receptor Information
>6czz Chain B (length=360) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARVFNFAAGPATLPENVLLKAQADLYNWRGSGMSVMEMSHRGKEFLSIIQ
KAESDLRQLLEIPQEYSVLFLQGGATTQFAALPLNLCKSDDTVDFVVTGS
WGDKAVKEAKKYCKTNVIWSGKSEKYTKVPSFEELEQTPDAKYLHICANE
TIHGVEFKDYPVPKNGFLVADMSSNFCSKPVDVSKFGVIYGGAQKNVGPS
GVTIVIIRKDLIGNAQDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVF
EDLLEQGGLKEVEKKNQRKADLLYNAIEESNGFFRCPVEKSVRSLMNVPF
TLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVA
FMKDFQAKHA
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain6czz Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6czz Structural Analysis of Phosphoserine Aminotransferase (Isoform 1) FromArabidopsis thaliana- the Enzyme Involved in the Phosphorylated Pathway of Serine Biosynthesis.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		G144 A145 T146 W171 T221 D241 S243 Q264 K265
Binding residue
(residue number reindexed from 1)		G74 A75 T76 W101 T151 D171 S173 Q194 K195
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.52: phosphoserine transaminase.
Gene Ontology
Molecular Function
GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
Biological Process
GO:0006564 L-serine biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6czz, PDBe:6czz, PDBj:6czz
PDBsum6czz
PubMed30034403
UniProtQ96255|SERB1_ARATH Phosphoserine aminotransferase 1, chloroplastic (Gene Name=PSAT1)

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