Structure of PDB 6bxu Chain B Binding Site BS03

Receptor Information

>6bxu Chain B (length=311) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVG
GKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTV
YTEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYA
IENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTA
TVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQ
VHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHS
TLTLYIKVLDI

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6bxu Chain B Residue 903 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6bxu Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution	3.79 Å
Binding residue (original residue number in PDB)	E606 D656 E658 D691
Binding residue (residue number reindexed from 1)	E126 D176 E178 D211
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:6bxu, PDBe:6bxu, PDBj:6bxu
PDBsum	6bxu
PubMed	32963095
UniProt	Q99PJ1\|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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