Structure of PDB 5x9h Chain B Binding Site BS03

Receptor Information
>5x9h Chain B (length=426) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVLEEIHPQDLLALWDELKGEHRYVVLTLLPKAKAAEVLSHLSPEEQAEY
LKTLPPWRLREILEELSLDDLADALQAVRKEDPAYFQRLKDLLDPRTRAE
VEALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIY
VVDEKGRLKGVLSLRDLIVADPRTRVAEIMNPKVVYVRTDTDQEEVARLM
ADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDIHKLGAVDVPDLV
YSEAGPVALWLARVRWLVILILTGMVTSSILQGFESVLEAVTALAFYVPV
LLGTGGNTGNQSATLIIRALATRDLDLRDWRRVFLKEMGVGLLLGLTLSF
LLVGKVYWDGHPLLLPVVGVSLVLIVFFANLVGAMLPFLLRRLGVDPALV
SNPLVATLSDVTGLLIYLSVARLLLE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5x9h Chain B Residue 505 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5x9h ATP-dependent modulation of MgtE in Mg(2+) homeostasis
Resolution3.598 Å
Binding residue
(original residue number in PDB)		D91 D247
Binding residue
(residue number reindexed from 1)		D69 D225
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015095 magnesium ion transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0015693 magnesium ion transport
GO:1903830 magnesium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5x9h, PDBe:5x9h, PDBj:5x9h
PDBsum5x9h
PubMed28747715
UniProtQ5SMG8|MGTE_THET8 Magnesium transporter MgtE (Gene Name=mgtE)

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