Structure of PDB 5w7a Chain B Binding Site BS03

Receptor Information
>5w7a Chain B (length=407) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRP
DNWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDAAGAHFH
IPPEWLTVSQMSVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSI
YLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLDHPAIVIYA
MIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGL
AHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANET
LRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQ
PWELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEV
FGDQGGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5w7a Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5w7a Crystal structure of the mammalian lipopolysaccharide detoxifier.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D222 D226 N228 N230 I232 E244
Binding residue
(residue number reindexed from 1)		D54 D58 N60 N62 I64 E76
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w7a, PDBe:5w7a, PDBj:5w7a
PDBsum5w7a
PubMed29343645
UniProtO18823|AOAH_RABIT Acyloxyacyl hydrolase (Gene Name=AOAH)

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