Structure of PDB 5o6e Chain B Binding Site BS03

Receptor Information
>5o6e Chain B (length=513) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVA
VTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENI
GALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPV
SKDPNRPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGN
IDDETEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHI
FNAIDGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGS
LGKVIEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQKS
SVKEGFAKSDIGEPVSPLDSSVFDFMKRVVVLENIKRKEQLMQTIHQNSA
GKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWS
LSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRI
KAHQKVIDFYLTL
Ligand information
Ligand IDALF
InChIInChI=1S/Al.4FH/h;4*1H/q+3;;;;/p-4
InChIKeyUYOMQIYKOOHAMK-UHFFFAOYSA-J
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al-](F)(F)F
FormulaAl F4
NameTETRAFLUOROALUMINATE ION
ChEMBL
DrugBankDB04444
ZINC
PDB chain5o6e Chain B Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5o6e Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Resolution3.345 Å
Binding residue
(original residue number in PDB)		A260 K264 E342 Q381 R417 G709 R734
Binding residue
(residue number reindexed from 1)		A25 K29 E107 Q146 R182 G458 R483
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5o6e, PDBe:5o6e, PDBj:5o6e
PDBsum5o6e
PubMed29202194
UniProtP07271|PIF1_YEAST ATP-dependent DNA helicase PIF1 (Gene Name=PIF1)

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