Structure of PDB 5lrb Chain B Binding Site BS03

Receptor Information
>5lrb Chain B (length=843) Species: 112509 (Hordeum vulgare subsp. vulgare) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IDSSAIASNIQHHADFTPLFSPEHSSPLKAYHATAKSVFDSLIMNWNATY
DYYNKVNAKQAYYLSMEFLQGRALTNAIGNLELTGQYAEALKQLGHNLED
VASQEPDPALGNGGLGRLASCFLDSLATLNYPAWGYGLRYRYGLFKQIIT
KDGQEEVAENWLEMGNPWEIVRNDVSYPVKFYGKVVEGTDGRKHWIGGEN
IKAVAHDVPIPGYKTKTTNNLRLWSTTVPSQNFDLGAFNAGDHAKANEAH
LNAEKICHVLYPGDESSEGKILRLKQQYTLCSASLQDIISRFESRAGDSL
NWEDFPSKVAVQMNDTHPTLCIPELMRILMDIKGLSWNEAWSITERTVAY
TNHTVLPEALEKWSLDIMQKLLPRHVEIIETIDEELMNNIVSKYGTADIS
LLKQKLKDMRILDNVDLPASVAKLFIKELDPFAKYDPQFPRVVRMANLCV
VGGHSVNGVAEIHSEIVKQDVFNSFYEMWPTKFQNKTNGVTPRRWIRFCN
PELSTIISKWIGSDDWILNTDKLAGLKKFADDEDLQSEWRTAKRNNKMKV
VSLIRDKTGYIVSPDAMFDVQVKRIHEYKRQLLNILGIVYRYKKMKEMSA
KDRRKSFVPRVCIFGGKAFATYVQAKRIVKFITDVAATVNYDPDIGDLLK
VVFVPDYNVSVAETLIPASELSQHISTAGMEASGTSNMKFAMNGCLLIGT
LDGANVEIREEVGEENFFLFGAHAPEIAGLRQERAEGKFVPDLRFEEVKE
YVRSGVFGTSNYDELMGSLEGNEGYGRADYFLVGKDFPSYIECQEKVDEA
YRDQKLWTRMSILNTAGSPKFSSDRTIHEYAKDIWDISPVIMP
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain5lrb Chain B Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lrb Functional and structural characterization of plastidic starch phosphorylase during barley endosperm development.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H421 R699 S808 G809
Binding residue
(residue number reindexed from 1)		H353 R574 S683 G684
Annotation score2
Enzymatic activity
Catalytic site (original residue number in PDB) H421 K698 R699 K704 T810 K814
Catalytic site (residue number reindexed from 1) H353 K573 R574 K579 T685 K689
Enzyme Commision number 2.4.1.1: glycogen phosphorylase.
Gene Ontology
Molecular Function
GO:0004645 1,4-alpha-oligoglucan phosphorylase activity
GO:0008184 glycogen phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009266 response to temperature stimulus
GO:0009414 response to water deprivation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5lrb, PDBe:5lrb, PDBj:5lrb
PDBsum5lrb
PubMed28407006
UniProtF2E0G2

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