Structure of PDB 5jsk Chain B Binding Site BS03

Receptor Information
>5jsk Chain B (length=482) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGRTTIAIDPVTRIEGHLKAEVVVENGKVVDARLSGGMYRGFETILRGRD
PRDASQIVQRICGVCPTAHSTASVLALDEAFGAKVPNNGRITRNLIFGAN
YLQSHILHFYHLSAQDFVQGPDTAPFVPRFPKSDLRLSKELNKAGVDQYI
EALEVRRICHEMVALFGGRMPHVQGQVVGGATEIPTKEKLVEYAARFKKV
RDFVEQKYVPVVYTIGSKYKDMFKVGQGFKAALCVGAFPLDNSGKKHLFM
PGVYAKGKDMPFDPSKIKEYVKYSWFAEETTGLNYKEGKTIPAPDKAGAY
SFVKAPRYDGLSLEVGPLARMWVNNPELSPVGKKLLKDLFGISAKKFRDL
GEEAAFSLMGRHVARAEETYYMLGAIEGWLKEIKAGEDTVVMPAVPASAE
GTGFTEAPRGSLLHYVKVKDSKIDNYQIVSASLWNCNPRDDMGQRGAVEE
ALIGIPVDDIQNPVNVARLIRAFDPCLGCAVH
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain5jsk Chain B Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jsk The direct role of selenocysteine in [NiFeSe] hydrogenase maturation and catalysis.
Resolution0.95 Å
Binding residue
(original residue number in PDB)		E56 I441 H495
Binding residue
(residue number reindexed from 1)		E43 I428 H482
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) E28 C75 C78 H82 R422 S445 C489 C492
Catalytic site (residue number reindexed from 1) E15 C62 C65 H69 R409 S432 C476 C479
Enzyme Commision number 1.12.7.2: ferredoxin hydrogenase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008901 ferredoxin hydrogenase activity
GO:0016151 nickel cation binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5jsk, PDBe:5jsk, PDBj:5jsk
PDBsum5jsk
PubMed28319099
UniProtQ72AS3

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