Structure of PDB 5fnn Chain B Binding Site BS03

Receptor Information

>5fnn Chain B (length=208) Species: 83333 (Escherichia coli K-12)

YRDQPLGELALSIPRASALFRKYDMDYAAGGKQTLARAAARKELDVEVIE
AEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVERVHADKPSVP
KGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEHDE
AGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVL
FPRALAGE

Ligand information

• Ligand ID: O
• InChI: InChI=1S/H2O/h1H2
• InChIKey: XLYOFNOQVPJJNP-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: O
  CACTVS 3.341: [O]
• Formula: O
• Name: OXYGEN ATOM
• ChEMBL: CHEMBL1098659
• DrugBank: DB09145
• PDB chain: 5fnn Chain B Residue 2019

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5fnn Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
• Resolution: 2.09 Å
• Binding residue (original residue number in PDB): H129 E133 H204 E208
• Binding residue (residue number reindexed from 1): H117 E121 H192 E196
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.7.2.5: nitric-oxide reductase (cytochrome c).

Gene Ontology

Molecular Function

• GO:0005506 iron ion binding
• GO:0005515 protein binding
• GO:0046872 metal ion binding
• GO:0098809 nitrite reductase activity

Biological Process

• GO:0006979 response to oxidative stress
• GO:0030091 protein repair
• GO:0051409 response to nitrosative stress

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:5fnn, PDBe:5fnn, PDBj:5fnn
• PDBsum: 5fnn
• PubMed: 27246459
• UniProt: P69506|YTFE_ECOLI Iron-sulfur cluster repair protein YtfE (Gene Name=ytfE)