Structure of PDB 5e9s Chain B Binding Site BS03

Receptor Information

>5e9s Chain B (length=427) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LLRRYLDYPVLWKILWGLVLGAVFGLIAGHFGYAGAVKTYIKPFGDLFVR
LLKMLVMPIVLASLVVGAASISPARLGRVGVKIVVYYLATSAMAVFFGLI
VGRLFNVGANVNLGSGTGKAIEAQPPSLVQTLLNIVPTNPFASLAKGEVL
PVIFFAIILGIAITYLMNRNEERVRKSAETLLRVFDGLAEAMYLIVGGVM
QYAPIGVFALIAYVMAEQGVRVVGPLAKVVGAVYTGLFLQIVITYFILLK
VFGIDPIKFIRKAKDAMITAFVTRSSSGTLPVTMRVAEEEMGVDKGIFSF
TLPLGATINMDGTALYQGVTVLFVANAIGHPLTLGQQLVVVLTAVLASIG
TAGVPGAGAIMLAMVLQSVGLDLTPGSPVALAYAMILGIDAILDMGRTMV
NVTGDLAGTVIVAKTEKELDESKWISH

Ligand information

Ligand ID

InChI

InChI=1S/Na/q+1

InChIKey

FKNQFGJONOIPTF-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Na+]

Formula

Name

SODIUM ION

PDB chain

5e9s Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5e9s Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	S280 G309 A310 N313 N405 V406 D409
Binding residue (residue number reindexed from 1)	S276 G305 A306 N309 N401 V402 D405
Annotation score	3

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0015293	symporter activity

	Biological Process
GO:0046942	carboxylic acid transport
GO:0055085	transmembrane transport

	Cellular Component
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:5e9s, PDBe:5e9s, PDBj:5e9s
PDBsum	5e9s
PubMed	27830699
UniProt	Q5JID0

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