Structure of PDB 5co1 Chain B Binding Site BS03

Receptor Information
>5co1 Chain B (length=205) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVFDEPVYTVNVLENSPINTLVIDLNATDPDEVVYSFINFVSNLTKQMFK
IDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDIN
DNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKVQCRLQG
NVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFA
VKVTD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5co1 Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5co1 Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		N317 N319 D352 D354 N358 D404
Binding residue
(residue number reindexed from 1)		N100 N102 D135 D137 N141 D187
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5co1, PDBe:5co1, PDBj:5co1
PDBsum5co1
PubMed27787195
UniProtF8W3X3|PCD19_DANRE Protocadherin-19 (Gene Name=pcdh19)

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