Structure of PDB 4wmq Chain B Binding Site BS03

Receptor Information
>4wmq Chain B (length=281) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WTCSLPRSCKEIKDECPSAFDGLYFLRTENGVIYQTFCDMTSGGGGWTLV
ASVHENDMRGKCTVGDRWSSQQGSKAVYPEGDGNWANYNTFGSAEAATSD
DYKNPGYYDIQAKDLGIWHVPNKSPMQHWRNSSLLRYRTDTGFLQTLGHN
LFGIYQKYPVKYGEGKCWTDNGPVIPVVYDFGDAQKTASYYSPYGQREFT
AGFVQFRVFNNERAANALCAGMRVTGCNTEHHCIGGGGYFPEASPQQCGD
FSGFDWSGYGTHVGYSSSREITEAAVLLFYR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4wmq Chain B Residue 403 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4wmq Recognition of microbial glycans by human intelectin-1.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		N260 E262 E274
Binding residue
(residue number reindexed from 1)		N228 E230 E242
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070492 oligosaccharide binding
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0009624 response to nematode
GO:0046326 positive regulation of D-glucose import
GO:0070207 protein homotrimerization
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0031526 brush border membrane
GO:0043235 receptor complex
GO:0045121 membrane raft
GO:0070062 extracellular exosome
GO:0098552 side of membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4wmq, PDBe:4wmq, PDBj:4wmq
PDBsum4wmq
PubMed26148048
UniProtQ8WWA0|ITLN1_HUMAN Intelectin-1 (Gene Name=ITLN1)

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