Structure of PDB 4m2z Chain B Binding Site BS03

Receptor Information

>4m2z Chain B (length=218) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFFIV
DLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKINE
TIIGDVFEALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKKDY
KTILQEITQKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGKSK
KEAEQRAAEELIKLLEES

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

4m2z Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4m2z RNase III: Genetics and Function; Structure and Mechanism.
Resolution	2.85 Å
Binding residue (original residue number in PDB)	D44 E110
Binding residue (residue number reindexed from 1)	D42 E108
Annotation score	4

Enzymatic activity

Enzyme Commision number

3.1.26.3: ribonuclease III.

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003725	double-stranded RNA binding
GO:0004519	endonuclease activity
GO:0004525	ribonuclease III activity
GO:0042802	identical protein binding
GO:0046872	metal ion binding

	Biological Process
GO:0006364	rRNA processing
GO:0006396	RNA processing
GO:0006397	mRNA processing
GO:0008033	tRNA processing
GO:0010468	regulation of gene expression

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:4m2z, PDBe:4m2z, PDBj:4m2z
PDBsum	4m2z
PubMed	24274754
UniProt	O67082\|RNC_AQUAE Ribonuclease 3 (Gene Name=rnc)

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