Structure of PDB 4la7 Chain B Binding Site BS03

Receptor Information
>4la7 Chain B (length=298) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLMHLTGHFFGVYDGHG
GHKVADYCRDRLHFALAEEIERIKDELCRQVQWDKVFTSCFLTVDGEIEG
KIGRAVDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEA
MPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKP
YVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKK
NGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4la7 Chain B Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4la7 Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		D243 D346 S347 S431 D432
Binding residue
(residue number reindexed from 1)		D47 D139 S140 S224 D225
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:4la7, PDBe:4la7, PDBj:4la7
PDBsum4la7
PubMed23818638
UniProtQ9CAJ0|P2C16_ARATH Protein phosphatase 2C 16 (Gene Name=HAB1)

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