Structure of PDB 4esj Chain B Binding Site BS03

Receptor Information
>4esj Chain B (length=241) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNHFEVADF
YCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYTKN
FEVNNFLVLPKQFVTPKSIIQRKPWIGCNIDLSQVPSKGRIFLVQDGQVR
DPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFE
SDLKNIFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4esj Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4esj Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		C34 C37 C56 C59
Binding residue
(residue number reindexed from 1)		C34 C37 C52 C55
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:4esj, PDBe:4esj, PDBj:4esj
PDBsum4esj
PubMed22610857
UniProtP0A460|T2D1_STRR6 Type II Methyl-directed restriction enzyme DpnI (Gene Name=dpnC)

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