Structure of PDB 4bnd Chain B Binding Site BS03

Receptor Information

>4bnd Chain B (length=253) Species: 416870 (Lactococcus cremoris subsp. cremoris MG1363)

AMKKILSFDIDNTLNEPKMPIFPEMAELLATLSQKYIIAPISGQKYDQFL
IQIINNLPESANLDNFHLFVAQGTQYYAHKAGEWKQVFNYALTDEQANAI
MGALEKAAKELGHWDESVLLPGDEINENRESMIAYSAIGQKAGVEAKQAW
DPDMTKRNEIAKLASQYAPEFEFEVAGTTTINGFVPGQNKEFGMNHLMEE
LNVTKEEILYFGDMTQPGGNDYPVVQMGIETITVRDWKETAAILKAIIAM
EEA

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 4bnd Chain B Residue 1257

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4bnd High-Resolution Structure of an Atypical [Alpha]-Phosphoglucomutase Related to Eukaryotic Phosphomannomutases
• Resolution: 1.5 Å
• Binding residue (original residue number in PDB): K146 G176 T177 T178 T179
• Binding residue (residue number reindexed from 1): K147 G177 T178 T179 T180
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 5.4.2.8: phosphomannomutase.

Gene Ontology

Molecular Function

• GO:0004615 phosphomannomutase activity
• GO:0016791 phosphatase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006013 mannose metabolic process
• GO:0006487 protein N-linked glycosylation
• GO:0009298 GDP-mannose biosynthetic process

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:4bnd, PDBe:4bnd, PDBj:4bnd
• PDBsum: 4bnd
• PubMed: 24100319
• UniProt: A2RIP9