Structure of PDB 4a36 Chain B Binding Site BS03

Receptor Information
>4a36 Chain B (length=523) Species: 8839 (Anas platyrhynchos) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKKARSYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGR
KAKVVFLATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIE
DSDIIVVTPQILVNSFEDGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTR
YLEQKFNSASQLPQILGLTASVGVGNAKNIEETIEHICSLCSYLDIQAIS
TVRENIQELQRFMNKPEIDVRLVKRRIHNPFAAIISNLMSETEALMRTIY
SFGTQNYEHWIVVTQRKCRSRICRALFICTEHLRKYNDALIISEDARIID
ALSYLTEFFTNVKNGPYTELEQHLTAKFQEKEPELIALSKDETNENPKLE
ELVCILDDAYRYNPQTRTLLFAKTRALVSALKKCMEENPILNYIKPGVLM
GRGMTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSG
NVTKMIQVRGRGRAAGSKCILVTSKTEVVENEKCNRYKEEMMNKAVEKIQ
KWDEETFAKKIHNLQMKERVLRD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4a36 Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		K302 V303 G329 T350 Q352 N356 H512 R519 K636 T637 R638 M663 T698 S699 V700
Binding residue
(residue number reindexed from 1)		K60 V61 G87 T108 Q110 N114 H259 R266 K373 T374 R375 M400 T428 S429 V430
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:4a36, PDBe:4a36, PDBj:4a36
PDBsum4a36
PubMed22000019
UniProtD3TI84

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