Structure of PDB 3w6p Chain B Binding Site BS03

Receptor Information
>3w6p Chain B (length=342) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPMEALIPVINKLQDVFNTVGADIIQLPQIVVVGTQSSGKSSVLESLVGR
DLLPRGTGIVTRRPLILQLVHVSQEDKRVEAEEWGKFLHTKNKLYTDFDE
IRQEIENETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVG
DQPKDIELQIRELILRFISNPNSIILAVTAANTDMATSEALKISREVDPD
GRRTLAVITKLDLMDAGTDAMDVLMGRVIPVKLGIIGVVNRSQLDINNKK
SVTDSIRDEYAFLQKKYPSLANRNGTKYLARTLNRLLMHHIRDCLPELKT
RINVLAAQYQSLLNRRKEAADMLKALQGASQIIAEIRETHLW
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3w6p Chain B Residue 803 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3w6p Crystal structure of GTPase domain fused with minimal stalks from human dynamin-1-like protein (Dlp1) in complex with several nucleotide analogues
Resolution1.7 Å
Binding residue
(original residue number in PDB)		S39 T59
Binding residue
(residue number reindexed from 1)		S41 T61
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.5: dynamin GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3w6p, PDBe:3w6p, PDBj:3w6p
PDBsum3w6p
PubMed
UniProtO00429|DNM1L_HUMAN Dynamin-1-like protein (Gene Name=DNM1L)

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