Structure of PDB 3t5t Chain B Binding Site BS03

Receptor Information
>3t5t Chain B (length=475) Species: 264445 (Streptomyces hygroscopicus subsp. limoneus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSEIFLASKRAAITYDTDPATGEPRAWLAPGGTGNVVAEQAGVLNISWIA
SADSEDDRRASALNPDGVTMELHSGREILVRLIRHDPAVFRNVQNFMTAN
LMWAANNYGWDRWTQPSFGSDAREGWADFGRFTRDFADAILKSSAQSADP
VYLVHDYQLVGVPALLREQRPDAPILLFVHIPWPSADYWRILPKEIRTGI
LHGMLPATTIGFFADRWCRNFLESVADLLPDARIDREAMTVEWRGHRTRL
RTMPLGYSPLTLPQLPEGIEEWADGHRLVVHSGRTDPIKNAERAVRAFVL
AARGGGLEKTRMLVRMNPNRLYVPANADYVHRVETAVAEANAELGSDTVR
IDNDNDVNHTIACFRRADLLIFNSTVDGQNLSTFEAPLVNERDADVILSE
TCGAAEVLGEYCRSVNPFDLVEQAEAISAALAAGPRQRAEAAARRRDAAR
PWTLEAWVQAQLDGLAADHAARTAT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3t5t Chain B Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3t5t Structural basis for the substrate specificity of ValL
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D55 D59
Binding residue
(residue number reindexed from 1)		D53 D57
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H182 D383
Catalytic site (residue number reindexed from 1) H180 D377
Enzyme Commision number 2.5.1.135: validamine 7-phosphate valienyltransferase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005992 trehalose biosynthetic process
GO:0017000 antibiotic biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3t5t, PDBe:3t5t, PDBj:3t5t
PDBsum3t5t
PubMed
UniProtQ15JG1|VLDE_STRHL Validamine 7-phosphate valienyltransferase (Gene Name=vldE)

[Back to BioLiP]