Structure of PDB 3psn Chain B Binding Site BS03

Receptor Information

>3psn Chain B (length=182) Species: 10090 (Mus musculus)

MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLK
TLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLA
LLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSF
VLMDIQASTVVTYVYQLIGDDVKVERIEYKKS

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 3psn Chain B Residue 703

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3psn Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): E123 K180
• Binding residue (residue number reindexed from 1): E123 K180
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.1.3.3: phosphoserine phosphatase.

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006896 Golgi to vacuole transport
• GO:0015031 protein transport
• GO:0032456 endocytic recycling
• GO:0042147 retrograde transport, endosome to Golgi

Cellular Component

• GO:0005737 cytoplasm
• GO:0005768 endosome
• GO:0005829 cytosol
• GO:0010008 endosome membrane
• GO:0016020 membrane
• GO:0030904 retromer complex
• GO:0030906 retromer, cargo-selective complex
• GO:0043231 intracellular membrane-bounded organelle

External links

• PDB: RCSB:3psn, PDBe:3psn, PDBj:3psn
• PDBsum: 3psn
• UniProt: Q9QZ88|VPS29_MOUSE Vacuolar protein sorting-associated protein 29 (Gene Name=Vps29)