Structure of PDB 3l7m Chain B Binding Site BS03

Receptor Information
>3l7m Chain B (length=411) Species: 176279 (Staphylococcus epidermidis RP62A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFKVNQFRKTLRHVKNIVLRRKNKERSLYDLTDKEDNVKPKTIVFESFGG
KNYSDSPKYIYEYMQKYYPNYRYIWSFKNPDKNVVPGSAEKVKRNSAEYY
QAYSEASHWVSNARTPLYLNKKENQTYIQTWHGTPLKRLANDMKVVRMPG
TTTPKYKRNFNRETSRWDYLISPNRYSTEIFRSAFWMDEERILEIGYPRN
DVLVNRANDQEYLDEIRTHLNLPSDKKVIMYAPTWRDDEFVSKGKYLFEL
KIDLDNLYKELGDDYVILLRMAYLISNALDLSGYENFAIDVSNYNDVSEL
FLISDCLITDYSSVMFDYGILKRPQFFFAYDIDKYDKGLRGFYMNYMEDL
PGPIYTEPYGLAKELKNLDKVQQQYQEKIDAFYDRFCSVDNGKASQYIGD
LIHKDIKEQLE
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain3l7m Chain B Residue 731 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3l7m Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis.
Resolution2.85 Å
Binding residue
(original residue number in PDB)		K449 T546 S624 S625
Binding residue
(residue number reindexed from 1)		K137 T234 S312 S313
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.8.12: teichoic acid poly(glycerol phosphate) polymerase.
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0047355 CDP-glycerol glycerophosphotransferase activity
Biological Process
GO:0019350 teichoic acid biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3l7m, PDBe:3l7m, PDBj:3l7m
PDBsum3l7m
PubMed20400947
UniProtQ5HLM5|TAGF_STAEQ Teichoic acid poly(glycerol phosphate) polymerase (Gene Name=tagF)

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